ZOSTRIX HP Topical Analgesic Cream 45g


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Zostrix HP Topical Analgesic Cream is a topical analgesic cream made from purified capsaicin, a natural extract from chili peppers. Capsaicin is believed to act on a substance in the body which is involved in transmission of pain impulses, known as Substance P. It is believed that regular application of capsaicin (ZOSTRIX) to the affected area will in time reduce the amount of Substance P in nearby nerve endings. With less of Substance P present, pain may be less intense and in some cases there may be a cessation of pain.

Product Indications:

  • For the treatment of medically diagnosed painful diabetic neuropathy or postherpetic neuralgia (pain following shingles)

45g Cream



  1. Apply ZOSTRIX 3 to 4 times a day, every day. Apply just enough to cover the affected area (a small fingertip is usually enough)
  2. Massage ZOSTRIX cream into the skin on the front, back and sides of the affected area until no residue remains
  3. Unless treating hands, always wash hands thoroughly with soap and water after the application and avoid contact with sensitive areas, such as eyes

Wash hands immediately after application (unless treating hands), and:

  • Do not apply ZOSTRIX to broken, open or irritated skin.
  • Do not apply heat pads or have a hot shower immediately after application.
  • Avoid bandaging the area following application.
  • Avoid touching the eyes, mouth or other sensitive areas.

For best results, little and often is the rule to follow.

Application of ZOSTRIX sometimes causes a burning sensation.
The heat, discomfort or burning sensation experienced by some patients upon application is related to the way ZOSTRIX works. Do not be concerned. This sensation is thought to be related to the initial release of Substance P and discomfort generally diminishes after the first few days of continued use. Remember, ZOSTRIX works gradually so pain relief may take up to 4-6 weeks.


Capsaicin 0.075% w/w

Contains benzyl alcohol 1% w/w as a preservative.


Always read the label. Use only as directed.
For external use only. Keep out of reach of children.
If irritation occurs discontinue use and seek medical advice.
Do not apply to broken, cracked or irritated skin.
Do not apply inside mouth, ear, nose or genitals.
Avoid contact with eyes, lips or other sensitive areas.
Do not bandage tightly.
If condition worsens, or does not improve after 28 days, discontinue use of this product and consult your doctor.

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